abstract：:The antinociceptive response of mice to the amino acid L-arginine (L-ARG) has been attributed to either an opioid mechanism or a non-opioid but nitric oxide (NO)-dependent mechanism. Earlier it was reported that the mechanism of nitrous oxide-induced antinociception involved opioid components and was also dependent on...

journal_title：Brain research bulletin

authors： Chung E,Burke B,Bieber AJ,Doss JC,Ohgami Y,Quock RM

更新日期：2006-07-31 00:00:00

abstract：:The beta-galactosidase protein generated by the bacterial LacZ gene is widely used to map gene expression patterns. The ease of its use is only rivaled by green fluorescent protein, which can be used in combination with various other procedures such as immunocytochemistry, flow cytometry, or tract tracing. The beta-ga...

journal_title：Brain research bulletin

authors： Matei VA,Feng F,Pauley S,Beisel KW,Nichols MG,Fritzsch B

更新日期：2006-06-15 00:00:00

abstract：:The brain serotoninergic (5HTergic) system of epileptic subjects can influence their vulnerability to stress. We studied the putative dependency of 5HT neurotransmission parameters on emotional stress, and the presence, types and severity of seizures using rats with genetic generalized (absence and/or audiogenic) epil...

journal_title：Brain research bulletin

authors： Midzyanovskaya IS,Kuznetsova GD,van Luijtelaar EL,van Rijn CM,Tuomisto L,Macdonald E

更新日期：2006-05-31 00:00:00

abstract：:We investigated the likelihood that bradykinesia coexisted with levodopa-induced dyskinesias (LID) in 10 dyskinetic Parkinson's disease patients (DPD). Their motor performance was compared to that of 10 age/gender-matched non-dyskinetic patients (NDPD) and 10 healthy controls. Whole-body movement (WBM) and rapid alter...

journal_title：Brain research bulletin

authors： Ghassemi M,Lemieux S,Jog M,Edwards R,Duval C

更新日期：2006-05-15 00:00:00

abstract：:The effect of pretreatment of geranylgeranylacetone (GGA), an inducer of heat shock protein (HSP) 70, on responses in sleep and core body temperature (Tcore) against sleep deprivation (SD) was examined in rats. After 3 days of GGA or vehicle injection, a 6-h period of SD was performed. During the recovery period, both...

journal_title：Brain research bulletin

authors： Wada T,Sei H,Kusumoto K,Kitaoka K,Chikahisa S,Rokutan K,Morita Y

更新日期：2006-04-28 00:00:00

abstract：:Neurodevelopmental disorders such as autism and schizophrenia involve social interaction problems and poor mentalizing abilities, associated with abnormal regional cerebral activity. Similar problems may be present in aggressive personality disorders and psychopathy. This paper reviews brain imaging data from research...

journal_title：Brain research bulletin

authors： Anckarsäter H

更新日期：2006-04-14 00:00:00

abstract：:The present study aimed to investigate the effects of sleep deprivation (SD) on the dose-dependent stimulant effect of ethanol (ETOH) on the open-field behavior of female and male mice. Sleep-deprived (48 h, multiple platforms method) or home-cage control female mice were treated with saline (SAL) or 1.4, 1.8 or 2.2g/...

journal_title：Brain research bulletin

authors： Araujo NP,Andersen ML,Abílio VC,Gomes DC,Carvalho RC,Silva RH,Ribeiro Rde A,Tufik S,Frussa-Filho R

更新日期：2006-04-14 00:00:00

abstract：:This study aimed to assess whether changes in the patterns of local field potential (LFP) oscillations of the subthalamic nucleus (STN) underlie to the clinical improvement within 60 s after turning off subthalamic DBS. We studied by spectral analysis the STN LFPs recorded in 13 nuclei from 7 patients with Parkinson's...

journal_title：Brain research bulletin

authors： Foffani G,Ardolino G,Egidi M,Caputo E,Bossi B,Priori A

更新日期：2006-03-31 00:00:00

abstract：:In a previous study we showed that healthy highly hypnotizable subjects, during the suggestion of a moderately unpleasant situation administered in awake conditions, exhibited a sympathetic response greatly attenuated with respect to non-hypnotizable individuals. This was interpreted as a natural protection of hypnoti...

journal_title：Brain research bulletin

authors： Gemignani A,Sebastiani L,Simoni A,Santarcangelo EL,Ghelarducci B

更新日期：2006-03-31 00:00:00

abstract：:Nutritional factors and nutritional deficiencies have been repeatedly associated with cognitive impairment. Most of the evidence is based on cross-sectional studies, which cannot prove whether a nutritional deficit is the cause or the consequence of an impaired cognitive status. In fact, cognitive impairment, in turn,...

journal_title：Brain research bulletin

authors： Del Parigi A,Panza F,Capurso C,Solfrizzi V

更新日期：2006-03-15 00:00:00

abstract：:On the basis of the evidence that approximately 45% of Schaffer collateral boutons are zinc-positive, zinc release from Schaffer collaterals and its action were examined in hippocampal slices. When zinc release from Schaffer collaterals was examined using ZnAF-2, a membrane-impermeable zinc indicator, ZnAF-2 signal in...

journal_title：Brain research bulletin

authors： Takeda A,Nakajima S,Fuke S,Sakurada N,Minami A,Oku N

更新日期：2006-02-15 00:00:00

abstract：:High dietary salt intake activates the brain renin-angiotensin system in spontaneously hypertensive rats (SHR) and Dahl S rats, resulting in sympathetic hyperactivity and hypertension. Increases of sodium concentration in cerebrospinal fluid (CSF) and/or enhanced responses to CSF sodium are considered to be involved i...

journal_title：Brain research bulletin

authors： Kubo T,Hagiwara Y

更新日期：2006-01-30 00:00:00

abstract：:The nucleus retroambiguus (NRA) is a group of neurons, located laterally in the caudal medulla oblongata. The NRA is thought to modulate abdominal pressure in the framework of respiration, vomiting, vocalization, probably parturition, and, in all likelihood mating behavior. The NRA exerts this control through its proj...

journal_title：Brain research bulletin

authors： Boers J,Kirkwood PA,de Weerd H,Holstege G

更新日期：2006-01-15 00:00:00

abstract：:Current treatments for Parkinson's disease (PD) rely on a dopamine replacement strategy and are reasonably effective, particularly in the early stages of the disease. However, chronic dopaminergic therapy is limited by the development of a range of side effects, including dyskinesia. This has led to a search for alter...

journal_title：Brain research bulletin

authors： Monville C,Torres EM,Dunnett SB

更新日期：2005-12-15 00:00:00

abstract：:Over the last 15 years, many publications described the use of peptide sequences that have been dubbed cell penetrating peptides (CPP), Trojan Horse peptides, protein transduction domains, or membrane-translocating sequences. These mostly positively charged domains bring attached cargo across biological membranes. One...

journal_title：Brain research bulletin

authors： Dietz GP,Bähr M

更新日期：2005-12-15 00:00:00

abstract：:It has been demonstrated that MK-801 potentiates the effects of the non-selective muscarinic antagonist scopolamine on memory in rats. In this study, we investigated the role of the M1-muscarinic receptor in this interaction, by administering different doses of dicyclomine (DIC) and MK-801 in combination to male Wista...

journal_title：Brain research bulletin

authors： Monteiro Moreira K,Lima Ferreira T,Vecchio Fornari R,Perez Figueredo LZ,Menezes Oliveira MG

更新日期：2005-11-30 00:00:00

abstract：:Until now, economic theory has not systematically integrated the influence of emotions on decision-making. Since evidence from neuroscience suggests that decision-making as hypothesized in economic theory depends on prior emotional processing, interdisciplinary research under the label of "neuroeconomics" arose. The k...

journal_title：Brain research bulletin

authors： Kenning P,Plassmann H

更新日期：2005-11-15 00:00:00

abstract：:From a psychophysiological point of view, arousal is a fundamental feature of behavior. As reported in different empirical studies based on insights from theories of consumer behavior, store atmosphere should evoke phasic arousal reactions to attract consumers. Most of these empirical investigations used verbal scales...

journal_title：Brain research bulletin

authors： Groeppel-Klein A

更新日期：2005-11-15 00:00:00

abstract：:The direct monosynaptic pathway which exists between vasoactive intestinal peptide (VIP) and GnRH neurons in the hypothalamic preoptic area provides a neuroanatomical background for the modulatory effects of VIP exerted on GnRH neurons activity. Though central microinjection of VIP revealed its involvement in the modu...

journal_title：Brain research bulletin

authors： Gajewska A,Wolińska-Witort E,Kochman K

更新日期：2005-10-30 00:00:00

abstract：:Acute inflammation activates macrophages or monocytes and subsequently releases several inflammatory cytokines and reactive oxygen and nitrogen species. These proinflammatory cytokines activate astrocytes and trigger neurodegenerative diseases. In this work, we chose to address the mechanistic aspects of alpha-crystal...

journal_title：Brain research bulletin

authors： Masilamoni JG,Vignesh S,Kirubagaran R,Jesudason EP,Jayakumar R

更新日期：2005-10-15 00:00:00

abstract：:Nine healthy subjects standing upright, initiated small, medium and large (S, M and L conditions, respectively) forward movements of their right (Rt) arm together with backward movements of their left (Lt) arm. They also performed medium-size movements while holding a 3 kg dumbbell in each hand (D condition). Movement...

journal_title：Brain research bulletin

authors： Yamazaki Y,Suzuki M,Ohkuwa T,Itoh H

更新日期：2005-09-30 00:00:00

abstract：:Neural progenitors in the subgranular zone of the hippocampal formation form a continuously proliferating cell population, generating new granule neurons throughout adult life. Between 10 days and 1 month after their formation, many of the newly generated cells die. The present study investigated whether a partial les...

journal_title：Brain research bulletin

authors： Van der Borght K,Mulder J,Keijser JN,Eggen BJ,Luiten PG,Van der Zee EA

更新日期：2005-09-30 00:00:00

abstract：:The olfactostriatum is a portion of the basal ganglia of snakes situated ventromedially to the nucleus accumbens proper. It receives a major vomeronasal input from the nucleus sphericus, the primary target of accessory olfactory bulb efferents. Recently, the ophidian olfactostriatum has been characterized on the basis...

journal_title：Brain research bulletin

authors： Martinez-Marcos A,Ubeda-Bañon I,Lanuza E,Halpern M

更新日期：2005-09-15 00:00:00

abstract：:Pax6 is a highly conserved transcription factor essential for the development of the eyes in vertebrate and invertebrate species. It is also required for normal development of many regions of the central nervous system, including the mammalian forebrain, hindbrain and spinal cord. In the forebrain, it is expressed in ...

journal_title：Brain research bulletin

authors： Manuel M,Price DJ

更新日期：2005-09-15 00:00:00

abstract：:As human brain development proceeds, there are complex changes in size and shape, most notably in the developing forebrain. Molecular technologies enable us to characterise the gene expression patterns that underlie these changes. To interpret these patterns the location of expression must be identified and, often, ge...

journal_title：Brain research bulletin

authors： Sarma S,Kerwin J,Puelles L,Scott M,Strachan T,Feng G,Sharpe J,Davidson D,Baldock R,Lindsay S

更新日期：2005-09-15 00:00:00

abstract：:Comparative studies on developmental gene expression suggest that the ancestral chordate central nervous system comprised anterior, midbrain-hindbrain boundary (MHB) and posterior regions. The most anterior region consists of both forebrain and midbrain in vertebrates. It remains, however, unresolved when or how the v...

journal_title：Brain research bulletin

authors： Takahashi T

更新日期：2005-09-15 00:00:00

abstract：:The development of dopamine-immunoreactive (DAir) populations in the central nervous system of the sea lamprey, a modern representative of the earliest vertebrates, was studied to achieve further understanding of dopaminergic systems in vertebrates. The first DAir cell groups appeared in the spinal cord, the posterior...

journal_title：Brain research bulletin

authors： Abalo XM,Villar-Cheda B,Anadón R,Rodicio MC

更新日期：2005-09-15 00:00:00

abstract：:Glutamate was found to be an excitatory neurotransmitter in the enteric nervous system. Although several lines of evidence indicate a role of glutamate in the regulation of gut motility and secretion the physiological significance of glutamatergic transmission is not clear yet. We studied the effect of glutamate on [3...

journal_title：Brain research bulletin

authors： Milusheva EA,Kuneva VI,Itzev DE,Kortezova NI,Sperlagh B,Mizhorkova ZN

更新日期：2005-08-15 00:00:00

abstract：:We investigated whether a continuous supply of glial cell line-derived neurotrophic factor (GDNF) via encapsulated genetically modified cells can promote survival and fiber outgrowth from xenotransplanted human dopaminergic neurons. Cells genetically engineered to continuously secrete GDNF were confined in hollow fibe...

journal_title：Brain research bulletin

authors： Ahn YH,Bensadoun JC,Aebischer P,Zurn AD,Seiger A,Björklund A,Lindvall O,Wahlberg L,Brundin P,Kaminski Schierle GS

更新日期：2005-07-30 00:00:00

abstract：:The analysis of physiological processes in brain by position emission tomography (PET) is facilitated when images are spatially normalized to a standard coordinate system. Thus, PET activation studies of human brain frequently employ the common stereotaxic coordinates of Talairach. We have developed an analogous stere...

journal_title：Brain research bulletin

authors： Andersen F,Watanabe H,Bjarkam C,Danielsen EH,Cumming P,DaNeX Study Group.

更新日期：2005-07-15 00:00:00

abstract：:Chronic swimming training and phytotherapeutic supplementation are assumed to alleviate oxidative damage, and support cell survival in the brain. The effect of forced, chronic swimming training, and enriched lab chow containing 1% (w/w) dried nettle (Urtica dioica) leaf were investigated for oxidative stress, inflamma...

journal_title：Brain research bulletin

authors： Toldy A,Stadler K,Sasvári M,Jakus J,Jung KJ,Chung HY,Berkes I,Nyakas C,Radák Z

更新日期：2005-05-30 00:00:00

abstract：:Insulin-like growth factor-1 (IGF-1) and growth hormone (GH) have been suggested to promote memory and cognitive capabilities. In a recent publication we observed that GH increase the proportion of the NR2B subunit mRNA transcript of the NMDA receptor in rat hippocampus. NR2B has been suggested to be essential for spa...

journal_title：Brain research bulletin

authors： Le Grevès M,Le Grevès P,Nyberg F

更新日期：2005-05-15 00:00:00

abstract：:Interleukin-1beta (IL-1beta), a cytokine with pronounced central effects such as fever, anorexia, analgesia, etc., is also known to activate the hypothalamo-pituitary-adrenal (HPA) axis. Corticotropin releasing hormone (CRH) neurons located in the hypothalamus are important for HPA activation. The cell bodies of CRH n...

journal_title：Brain research bulletin

authors： MohanKumar SM,MohanKumar PS

更新日期：2005-05-15 00:00:00

abstract：:Here we have investigated whether differences in levels of dopamine D1-like, D2-like receptors, dopamine D3 receptors, and dopamine transporter could be related to behaviors such as immobility response and locomotion between Wistar rats and Sprague-Dawley rats. The levels of the dopamine receptors and transporter were...

journal_title：Brain research bulletin

authors： Zamudio S,Fregoso T,Miranda A,De La Cruz F,Flores G

更新日期：2005-04-30 00:00:00

abstract：:This paper provides an introduction to a special issue dedicated to the action of environmental estrogens on neural circuits and behavior. The problem of endocrine disrupting chemicals (EDCs), i.e. chemicals that have the capacity to interfere with the endocrine system, has gained increasing attention as it has become...

journal_title：Brain research bulletin

authors： Panzica GC,Viglietti-Panzica C,Ottinger MA

更新日期：2005-04-15 00:00:00

abstract：:Play behavior is affected by alteration of the hormonal environment during development. In fact, congenital adrenal hyperplasia or early administration of diethylstilbestrol are able to modify female play behavior in mammals. In this research, play behavior of female rats was used to explore the effects of perinatal e...

journal_title：Brain research bulletin

authors： Porrini S,Belloni V,Della Seta D,Farabollini F,Giannelli G,Dessì-Fulgheri F

更新日期：2005-04-15 00:00:00

abstract：:There is growing evidence that Vitamin D(3) (1,25-dihydroxyvitamin D(3)) is involved in brain development. We have recently shown that the brains of newborn rats from Vitamin D(3) deficient dams were larger than controls, had increased cell proliferation, larger lateral ventricles, and reduced cortical thickness. Brai...

journal_title：Brain research bulletin

authors： Féron F,Burne TH,Brown J,Smith E,McGrath JJ,Mackay-Sim A,Eyles DW

更新日期：2005-03-15 00:00:00

abstract：:The aim of the present study was to investigate the effects of activation of metabotropic glutamate receptors (mGluR) on the extracellular concentrations of GABA and acetylcholine in the prefrontal cortex of freely moving rats of different groups of age. Perfusion, through the microdialysis probe, of the agonist of mG...

journal_title：Brain research bulletin

authors： Segovia G,Mora F

更新日期：2005-02-15 00:00:00

abstract：:The alpha-2 adrenoreceptor agonist clonidine in low dose inhibits the release of noradrenaline and aggravates absence seizures. The present study examines properties of two types of spike-wave discharges (SWD) in a genetic model of absence epilepsy, the WAG/Rij rats. After reduction of noradrenergic neurotransmission ...

journal_title：Brain research bulletin

authors： Sitnikova E,van Luijtelaar G

更新日期：2005-01-30 00:00:00

abstract：:The central nervous system (CNS) histaminergic neurons have been shown to regulate feeding behavior and are a target of leptin in the brain. The present study aimed to examine the involvement of the histaminergic system in the leptin-mediated regulation of cardiovascular dynamics. We investigated the cardiovascular re...

journal_title：Brain research bulletin

authors： Rao SP,Dunbar JC

更新日期：2005-01-15 00:00:00